Metabolomic fingerprinting and systemic inflammatory profiling of asthma COPD overlap (ACO)
نویسندگان
چکیده
منابع مشابه
Inflammatory biomarkers in asthma-COPD overlap syndrome
BACKGROUND The clinical phenotypes and underlying mechanisms of asthma-COPD overlap syndrome (ACOS) remain elusive. This study aimed to investigate a comparison of COPD patients with and without ACOS, focusing on inflammatory biomarkers, in an outpatient COPD cohort. METHODS We conducted a cross-sectional study analyzing prospectively collected data from the Ishinomaki COPD Network registry. ...
متن کاملSystemic Inflammation in Older Adults With Asthma-COPD Overlap Syndrome
PURPOSE The role of systemic inflammation on asthma-COPD overlap syndrome is unknown. This study aimed to examine systemic inflammation in asthma-COPD overlap syndrome, and to identify associations between clinical characteristics and inflammatory mediators in asthma-COPD overlap syndrome. METHODS In 108 adults older than 55 years comprising healthy controls (n=29), asthma (n=16), COPD (n=21)...
متن کاملBurden of asthma and COPD overlap (ACO) in Taiwan: a nationwide population-based study
BACKGROUND Patients with symptoms of both asthma and chronic obstructive pulmonary disease (COPD) may be classified with the term asthma-COPD overlap (ACO). ACO is of considerable interest as it is currently poorly characterised and has been associated with worse health outcomes and higher healthcare costs compared with COPD or asthma alone. Patients with ACO in Asia remain poorly described, an...
متن کاملThe Asthma-COPD Overlap Syndrome.
Although in textbooks asthma and chronic obstructive pulmonary disease (COPD) are viewed as distinct disorders, there is increasing awareness that many patients have features of both. This article reviews the asthma-COPD overlap syndrome.
متن کاملThe Asthma-COPD Overlap Syndrome
Asthma and Chronic Obstructive Pulmonary Disease (COPD) are pulmonary disorders characterized by various degrees of airflow limitation, inflammation and tissue remodeling. Bronchial asthma, an allergic disease that develops in childhood, is physiologically characterized by reversible airflow obstruction. It has an episodic course and a generally favorable prognosis, as it responds well to anti-...
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ژورنال
عنوان ژورنال: Respiratory Research
سال: 2020
ISSN: 1465-993X
DOI: 10.1186/s12931-020-01390-4